The suppository is solid at room temperature, but melts at the normal body temperature (98.6°F).
For a suppository to completely melt in a healthy woman, it takes 15-20 minutes.
However, many women at and after menopause, their body temperatures fluctuate. When the body temperature goes up, it causes hot flash. When it goes down, you may not feel it and may be unaware of it. The only way to find out is to measure your temperature with a thermometer
In some postmenopausal women, their body temperature may drop several degrees below normal. As a result, it may take them longer time, like many hours, to melt a suppository.
One customer inserted the suppository during the day. After a little while, she started walking around. The unmelt suppository fell out. After she inserted the suppository at bedtime, she had no more problem.
Thus, for best result, we recommend that you apply the suppository at the bedtime. It will allow sufficient time for the suppository to melt.
Even if your body temperature is normal, remaining a laying down position will keep the suppository and its melt ingredients from leaking out for a whole night. This will allow maximal absorption of the suppository.