Study of LV-Clear for Clearing Lactobacillus iners-related Vaginosis (LV)

Announcement

Study of LV-Clear for Clearing Lactobacillus iners-related Vaginosis (LV)

What is L. iners-related Vaginosis?

L. iners-related vaginosis (LV) is a vaginal dysbiosis characterized by symptoms such as vaginal odor, discharge, burning, and irritation. These symptoms are similar to those of bacterial vaginosis (BV), but typical treatments for BV, such as metronidazole, are often ineffective. The vaginal microbiome lab test shows that the dominant bacterium is Lactobacillus iners. While the exact cause is unknown, it is believed to be linked to an imbalance in the vaginal microbiome. Unlike BV, which is dominated by anaerobic bacteria, LV is dominated by the Lactobacillus species, L. iners. This condition is becoming increasingly recognized due to the availability of vaginal microbiome tests based on the cutting-edge next-generation sequencing (NGS) technology.

Challenges in LV Treatment
LV is difficult to treat because L. iners belongs to the same genus as the beneficial Lactobacillus bacteria. Additionally, it can hide in the woman's bladder and the partner's bladder as reservoirs. After treatment, the surviving L. iners can emerge from these reservoirs, causing a recurrence. Currently, there have been no consistently effective treatments for LV.

What is LV Clear?
LV Clear is a vaginal suppository designed to clear L. iners-related vaginosis. Made with natural, food-grade ingredients, it contains carefully selected nutrients, including vitamins, minerals, and herbal extracts.

Study Details

  • Eligibility: Women with LV, aged 18–70, who are otherwise healthy (no cancer, organ transplants, pregnancy, or breastfeeding) and reside in the U.S.
  • Cost: A $120 deposit is required to ensure study completion. One pack of LV Clear costs $88 for 6 suppositories, and 1 bottle of Vaginal Probiotic costs $38. After completing the study and submitting feedback plus an after-treatment microbiome test from the same lab of your test, you will be refunded $120, making the net product cost zero.
  • Diagnosis: Participants must have a diagnosis of LV based on the lab test report showing Lactobacillus iners dominance.
  • Tracking: Record daily symptom changes in a journal using a few words with a simple template table.
  • Study Duration: 12 days. Insert an LV Clear suppository on the first day and insert a Vaginal Probiotic capsule the next day, and repeat it 6 times for a total of 12 days.
  • Product Use: Use only the new product LV Clear and the NeuEve brand Vaginal Probiotic capsules for the study to clear LV. However, if you are taking products for other conditions like diabetes, hypertension, or arthritis, you may continue using them. For clearing the vaginal LV condition, you must use LV Clear and the NeuEve brand Vaginal Probiotic, not other vaginal care products.
  • Benefits of Joining: You may have the opportunity to clear stubborn LV at no cost when other treatments have failed. If it doesn’t work the first time, you can join additional rounds of the study for free until your LV symptoms subside. By participating, you’ll help develop the first natural product dedicated to LV relief and contribute to advancing women's health.
  • Sign Up: We are accepting 10 volunteers on a first-come, first-served basis. If interested, email us at help@neueve.com.
Feb 1, 2026

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