Dietary supplements for preventing recurrent UTIs

Antibiotics are effective for short-term treatment of acute UTIs. However, for chronic recurrent UTIs, repeated use of antibiotics may cause side effects. These include induction of drug resistant bacteria (superbugs) and other unwanted side effects like yeast infection. Thus, it is desirable to treat chronic recurrent UTIs without using antibiotics. In addition to using NeuEve suppositories and balm cream, taking dietary supplements as a combination can also help prevent UTIs.

Certain dietary supplements are good for preventing chronic and recurrent UTIs. These include D-Mannosecranberry extract, and vitamin D.

1) D-Mannose
D-Mannose is a simple sugar. It forms a part of a structure on the cell surface. When the E. coli bacteria gets into the urinary tract, it latches onto the cells by binding to the mannose structure as a receptor, and to cause an infection. D-mannose, when consumed in foods, can prevent UTIs by blocking the E. coli bacteria from attaching to the cell surface.


D-mannose is effective in preventing UTIs. However, it is a type of sugar and may increase blood sugar level after consumption. Thus, it should be used with caution if you have diabetes.

2) Cranberry Extract
Cranberry juice or extract has been used to prevent UTIs. Researchers showed that cranberry contains a high level of polyphenols that can block the adherence of bacteria to the bladder, thereby reduce UTI infections.

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Cranberry juice is a tasty soft drink. You can drink it safely without a health concern if you do not have diabetes. However, if you are diabetic, you will need to consume cranberry juice with caution. Many cranberry juice products claim "no sugar added." But the juice has already a high level of sugar from the berry itself. For those who have diabetes, the cranberry extract pills is a safer alternative.

3) Vitamin D3
Vitamin C (ascorbic acid) was thought to prevent UTIs. However, after repeated studies, researchers could not find evidence that vitamin C works.
The only vitamin that is well documented to boost resistance against UTIs is vitamin D3. First, studies have shown that vitamin D deficiency make women susceptible to recurrent UTIs. Second, vitamin D was found to induce an antimicrobial peptide cathelicidin in the urinary bladder. This peptide in turn can kill the E. coli bacteria to prevent UTIs. Thus, taking vitamin D3 can be a good dietary supplement to prevent chronic recurrent UTIs.

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In summary, non-antibiotic methods to prevent recurrent UTIs include behavior changes, like drinking a lot of water and pee immediately after sex, using NeuEve suppositories and balm cream, and taking dietary supplements. Three dietary supplements can be used for preventing chronic UTIs, D-mannose, cranberry juice/extract, and vitamin D3. Combination of these methods was reported to have a synergistic effect against UTIs.

Note: We do not sell these supplements. We recommend them for your own health benefit.

Disclaimer: This article is for information purposes only. It is about natural products, nutrients, and/or methods for managing vaginal aging-related discomfort (not a true infection or disease). It is not medical advice for the treatment of any diseases.

Mar 18, 2022

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